De Novo Appearance ofthe Ph ’ Chromosome in a Previously Monosomic Bone Marrow
نویسندگان
چکیده
Bone marrow examination of a patient chromosome in the previously aneuploid with a myeloproliferative disorder recell line (45,XX,-6,-22,+Ph’). This case vealed monosomy for chromosome No. 6 differs from those previously published in (45,XX,-6). Two months later, during that the Ph’ chromosome appeared de blastic crisis, reinvestigation of the bone novo during the development of frank marrow showed the presence of the Ph’ acute myelogenous leukemia.
منابع مشابه
De novo appearance of the ph-1 chromosome in a previously monosomic bone marrow (45,XX,-6): conversion of a myeloproliferative disorder to acute myelogenous leukemia.
Bone marrow examination of a patient with a myeloproliferative disorder revealed monosomy for chromosome No. 6 (45,XX,-6). Two months later, during blastic crisis, reinvestigation of the bone marrow showed the presence of the Ph-1 chromosome in the previously aneuploid cell line (45,XX,-6,-22,+Ph-1). This case differs from those previously published in that the Ph-1 chromosome appeared de novo ...
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